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Article

Integrative analysis of copy number and transcriptional expression profiles in esophageal cancer to identify a novel driver gene for therapy

7 Feb 2017

Abstract excerpt

An increasing amount of evidence has highlighted the critical roles that copy number variants play in cancer progression. Here, we systematically analyzed the copy number alterations and differentially transcribed genes. Integrative analysis of the association between copy number variants and differential gene expression suggested that copy number variants will lead to aberrant expression of the corresponding...

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Share to Epigenetics and DNA Methylation
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PMID: 28169357
DOI: 10.1038/srep42060

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