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Article

MAFB promotes the malignant phenotypes by IGFBP6 in esophageal squamous cell carcinomas.

Experimental cell research - 1 Jul 2022

Zhang Shaobo, Gong Tongyang, Nan Yabin, Feng Riyue, Liu Zhihua, Chen Hongyan

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant diseases in the world. Although the somatic alterations have been fully identified, there are still no targeted drugs at present. Our previous studies revealed that loss of grand H3K27me3 domains mediated transcriptional activation of a series of genes in ESCC. Among them, we focus on the investigation of MAFB, as its high expression is...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

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Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 35430273
DOI: 10.1016/j.yexcr.2022.113158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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