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Article

Copy number loss of FBXW7 is related to gene expression and poor prognosis in esophageal squamous cell carcinoma

19 Apr 2012

Abstract excerpt

FBXW7 is a tumor suppressor gene that plays a role in cell cycle regulation via Myc degradation. However, the clinical significance of FBXW7 in esophageal squamous cell carcinoma (ESCC) has not been evaluated. The purpose of this study was to assess the clinical significance of FBXW7 for prognosis in human ESCC. Real-time RT-PCR was used to examine the expression of FBXW7 to determine its clinicopathological...

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PMID: 22576686
DOI: 10.3892/ijo.2012.1436

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