Article
The History of Bordetella pertussis Genome Evolution Includes Structural Rearrangement.
Journal of bacteriology - 15 Apr 2017
Weigand Michael R, Peng Yanhui, Loparev Vladimir, Batra Dhwani, Bowden Katherine E, Burroughs Mark, Cassiday Pamela K, Davis Jamie K, Johnson Taccara, Juieng Phalasy, Knipe Kristen, Mathis Marsenia H, Pruitt Andrea M, Rowe Lori, Sheth Mili, Tondella M Lucia, Williams Margaret M
Abstract excerpt
Despite high pertussis vaccine coverage, reported cases of whooping cough (pertussis) have increased over the last decade in the United States and other developed countries. Although Bordetella pertussis is well known for its limited gene sequence variation, recent advances in long-read sequencing technology have begun to reveal genomic structural heterogeneity among otherwise indistinguishable isolates, even...
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