Article
Bordetella pertussis evolution in the (functional) genomics era.
Pathogens and disease - 1 Nov 2015
Belcher Thomas, Preston Andrew
Abstract excerpt
The incidence of whooping cough caused by Bordetella pertussis in many developed countries has risen dramatically in recent years. This has been linked to the use of an acellular pertussis vaccine. In addition, it is thought that B. pertussis is adapting under acellular vaccine mediated immune selection pressure, towards vaccine escape. Genomics-based approaches have revolutionized the ability to resolve the fine...
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