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Article

Genomic Sequencing of Bordetella pertussis for Epidemiology and Global Surveillance of Whooping Cough.

Emerging infectious diseases - 1 Jun 2018

Bouchez Valérie, Guglielmini Julien, Dazas Mélody, Landier Annie, Toubiana Julie, Guillot Sophie, Criscuolo Alexis, Brisse Sylvain

Abstract excerpt

Bordetella pertussis causes whooping cough, a highly contagious respiratory disease that is reemerging in many world regions. The spread of antigen-deficient strains may threaten acellular vaccine efficacy. Dynamics of strain transmission are poorly defined because of shortcomings in current strain genotyping methods. Our objective was to develop a whole-genome genotyping strategy with sufficient resolution for...

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Identifiers

PMID: 29774847
DOI: 10.3201/eid2406.171464
PMCID: PMC6004856

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