Article
Acquisition and loss of virulence-associated factors during genome evolution and speciation in three clades of Bordetella species.
BMC genomics - 30 Sept 2016
Linz Bodo, Ivanov Yury V, Preston Andrew, Brinkac Lauren, Parkhill Julian, Kim Maria, Harris Simon R, Goodfield Laura L, Fry Norman K, Gorringe Andrew R, Nicholson Tracy L, Register Karen B, Losada Liliana, Harvill Eric T
Abstract excerpt
BACKGROUND: The genus Bordetella consists of nine species that include important respiratory pathogens such as the 'classical' species B. bronchiseptica, B. pertussis and B. parapertussis and six more distantly related and less extensively studied species. Here we analyze sequence diversity and gene content of 128 genome sequences from all nine species with focus on the evolution of virulence-associated factors....
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