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Article

Disruption ofpdgfraalters endocardial and myocardial fusion during zebrafish cardiac assembly

1 Jan 2017

Abstract excerpt

Cardiac development in vertebrates is a finely tuned process regulated by a set of conserved signaling pathways. Perturbations of these processes are often associated with congenital cardiac malformations. Platelet-derived growth factor receptor α (PDGFRα) is a highly conserved tyrosine kinase receptor, which is essential for development and organogenesis. Disruption of Pdgfrα function in murine models are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28167492
DOI: 10.1242/bio.021212

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