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Article

GWAS implicated risk variants in different genes contribute additively to increase the risk of coronary artery disease (CAD) in the Pakistani subjects.

Lipids in health and disease - 19 Apr 2018

Shahid Saleem Ullah, Shabana N A, Rehman Abdul, Humphries Steve

Abstract excerpt

BACKGROUND: Coronary artery disease (CAD) remains the single most important cause of mortality worldwide. Many candidate and GWAS genetic variants have been identified in the recent years. In the current study, we selected six SNPs from various genes that have originally been identified in GWAS studies and examined the association of SNPs individually and as a genetic risk score (GRS) with CAD and blood lipid...

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Source

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Identifiers

PMID: 29673405
DOI: 10.1186/s12944-018-0736-2
PMCID: PMC5909255

Genes

CAD
CXCL12
MIA3
MRAS
SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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