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Article

Association of APOB (rs515135) and PCSK9 (rs505151) gene polymorphisms with CAD in the Indian population.

Biomarkers in medicine - 1 May 2025

Eba Ale, Raza Syed Tasleem, Wani Irshad Ahmad, Ahmad Bashir, Abbas Mohammad, Siddiqi Zeba, Srivastava Sanchita, Mahdi Farzana

Abstract excerpt

INTRODUCTION: Coronary artery disease (CAD) is a multifactorial disorder influenced by both genetic and clinical risk factors. Lipid metabolism genes such as apolipoprotein B(APOB) (rs515135) and proprotein convertase subtilisin/kexin type 9 (PCSK9)(rs505151), have been associated with susceptibility to CAD. Study investigates the potential role of these genetic polymorphisms with risk of CAD in the Indian...

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Identifiers

PMID: 40270278
DOI: 10.1080/17520363.2025.2496128
PMCID: PMC12077466

Genes

CAD
APOB
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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