Article
Association Study of Coronary Artery Disease-Associated Genome-Wide Significant SNPs with Coronary Stenosis in Pakistani Population.
Disease markers - 1 Jan 2020
Cheema Asma Naseer, Pirim Dilek, Wang Xingbin, Ali Jabar, Bhatti Attya, John Peter, Feingold Eleanor, Demirci F Yesim, Kamboh M Ilyas
Abstract excerpt
Genome-wide association studies (GWAS) of coronary artery disease (CAD) have revealed multiple genetic risk loci. We assessed the association of 47 genome-wide significant single-nucleotide polymorphisms (SNPs) at 43 CAD loci with coronary stenosis in a Pakistani sample comprising 663 clinically ascertained and angiographically confirmed cases. Genotypes were determined using the iPLEX Gold technology. All...
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