Article
Genetic determinants of clinical heterogeneity of the coronary artery disease in the population of Hyderabad, India.
Human genomics - 4 Mar 2017
Pranavchand Rayabarapu, Kumar Arramraju Sreenivas, Reddy Battini Mohan
Abstract excerpt
BACKGROUND: Genetic predisposition to the clinical categories of coronary artery disease (anatomical viz., insignificant, single, double, and triple vessel diseases and phenotypic severity categories viz., angina, acute coronary syndrome, and myocardial infarction) is poorly understood. Particularly, the apolipoprotein genes clustered at 11q23.3 chromosomal region play a vital role in cholesterol homeostasis, and...
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