Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease.

doi:10.1053/j.gastro.2024.02.026

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Article

Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease.

Gastroenterology - 1 Jul 2024

Khrom Michelle, Long Millie, Dube Shishir, Robbins Lori, Botwin Gregory J, Yang Shaohong, Mengesha Emebet, Li Dalin, Naito Takeo, Bonthala Nirupama N, Ha Christina, Melmed Gil, Rabizadeh Shervin, Syal Gaurav, Vasiliauskas Eric, Ziring David, Brant Steven R, Cho Judy, Duerr Richard H, Rioux John, Schumm Phil, Silverberg Mark, Ananthakrishnan Ashwin N, Faubion William A, Jabri Bana, Lira Sergio A, Newberry Rodney D, Sandler Robert S, Xavier Ramnik J, Kugathasan Subra, Hercules David, Targan Stephan R, Sartor R Balfour, Haritunians Talin, McGovern Dermot P B

Abstract excerpt

BACKGROUND & AIMS: Patients with inflammatory bowel disease (IBD) frequently develop extraintestinal manifestations (EIMs) that contribute substantially to morbidity. We assembled the largest multicohort data set to date to investigate the clinical, serologic, and genetic factors associated with EIM complications in IBD. METHODS: Data were available in 12,083 unrelated European ancestry IBD cases with presence or...

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PMID: 38490347
DOI: 10.1053/j.gastro.2024.02.026
PMCID: PMC11193636

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