Article
The impact of viral RNA on the association free energies of capsid protein assembly: bacteriophage MS2 as a case study.
Journal of molecular modeling - 1 Feb 2017
ElSawy Karim M
Abstract excerpt
A large number of single-stranded RNA viruses assemble their capsid and their genomic material simultaneously. The RNA viral genome plays multiple roles in this process that are currently only partly understood. In this work, we investigated the thermodynamic basis of the role of viral RNA on the assembly of capsid proteins. The viral capsid of bacteriophage MS2 was considered as a case study. The MS2 virus...
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