Dissecting the key recognition features of the MS2 bacteriophage translational repression complex.

doi:10.1093/nar/26.5.1337

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Article

Dissecting the key recognition features of the MS2 bacteriophage translational repression complex.

Nucleic acids research - 1 Mar 1998

Lago H, Fonseca S A, Murray J B, Stonehouse N J, Stockley P G

Abstract excerpt

The MS2 RNA operator capsid offers an unparalleled opportunity to study sequence-specific protein-protein and RNA-protein interactions in molecular detail. RNA molecules encompassing the minimal translational operator recognition elements can be soaked into crystals of RNA-free coat protein shells, allowing the RNA to access the interior of the capsids and make contact with the operator binding sites. Correct...

Topics

Base Sequence
Binding Sites
Capsid
Capsid Proteins
Dimerization
Genetic Variation
Levivirus
Macromolecular Substances
Models, Molecular
Mutagenesis, Site-Directed
Nucleic Acid Conformation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Operator Regions, Genetic

Point Mutation

Protein Biosynthesis

Protein Conformation

RNA, Viral

RNA-Binding Proteins

Source

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Identifiers

PMID: 9469846
DOI: 10.1093/nar/26.5.1337
PMCID: PMC147387

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