Article
Dissecting the key recognition features of the MS2 bacteriophage translational repression complex.
Nucleic acids research - 1 Mar 1998
Lago H, Fonseca S A, Murray J B, Stonehouse N J, Stockley P G
Abstract excerpt
The MS2 RNA operator capsid offers an unparalleled opportunity to study sequence-specific protein-protein and RNA-protein interactions in molecular detail. RNA molecules encompassing the minimal translational operator recognition elements can be soaked into crystals of RNA-free coat protein shells, allowing the RNA to access the interior of the capsids and make contact with the operator binding sites. Correct...
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