Article

RNA-induced allosteric coupling drives viral capsid assembly in bacteriophage MS2

2023-06-06

Abstract excerpt

Understanding the mechanisms by which single-stranded RNA viruses regulate capsid assembly around their RNA genomes has become increasingly important for the development of both antiviral treatments and drug delivery systems. Here, we investigate the effects of RNA-induced allostery in a single-stranded RNA virus — Levivirus bacteriophage MS2 — using the computational methods of the Dynamic Flexibility Index (DFI...

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Literature Corpus work: 80a7e609-aaf3-52cb-822a-84bd71eda312
DOI: 10.1101/2023.06.05.543665

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