Article

Pathological characteristics of axons and proteome patterns in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency

2023-05-18

Abstract excerpt

<title>Abstract</title> Background Although <italic>WD repeats domain 45 (WDR45)</italic> mutations have been linked to \({\beta }\)-propeller protein-associated neurodegeneration (BPAN), the precise molecular and cellular mechanisms behind this disease remain elusive. This study aims to shed light on the effects of WDR45-deficiency on neurodegeneration, specifically axonal degeneration, within the midbrain d...

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Literature Corpus work: eba17b58-2cae-5e1f-a046-2ab129935e18
DOI: 10.21203/rs.3.rs-2901370/v1

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