Article
TNF-α differentially regulates cell cycle genes in promyelocytic and granulocytic HL-60/S4 cells
2018-11-19
Abstract excerpt
Tumor necrosis factor alpha (TNF-α) is a potent cytokine involved in systemic inflammation and immune modulation. Signaling responses that involve TNF-α are context dependent and capable of stimulating pathways promoting both cell death and survival. TNF-α treatment has been investigated as part of a combined therapy for acute myeloid leukemia due to its modifying effects on all-trans retinoic acid (ATRA) mediated...
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Identifiers and source
- Literature Corpus work
- 127abc2e-0215-59ad-87e0-752545e01a21
- DOI
- 10.1101/471789
