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Article

Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cells.

Gene - 1 Aug 2008

Mollinedo Faustino, López-Pérez Ricardo, Gajate Consuelo

Abstract excerpt

We have identified sequential changes in the gene expression pattern of human myeloid leukaemia HL-60 cells during their neutrophil differentiation induced by dimethyl sulfoxide (DMSO) that account for the acquisition of mature neutrophil phenotypic hallmarks. Following 1-day DMSO treatment, HL-60 cells were committed to neutrophil differentiation with loss of their proliferative capacity, and gene expression...

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Identifiers

PMID: 18547747
DOI: 10.1016/j.gene.2008.04.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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