Article
Genetic Methods for Studying Yeast Prions.
Cold Spring Harbor protocols - 1 Feb 2017
Wickner Reed B, Edskes Herman K, Kryndushkin Dmitry, Shewmaker Frank P
Abstract excerpt
The recognition that certain long-known nonchromosomal genetic elements were actually prions was based not on the specific phenotypic manifestations of those elements, but rather on their unusual genetic properties. Here, we outline methods of prion assay, methods for showing the nonchromosomal inheritance, and methods for determining whether a nonchromosomal trait has the unusual characteristics diagnostic of a...
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