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Article

Interactions between chromosomal and nonchromosomal elements reveal missing heritability.

Proceedings of the National Academy of Sciences of the United States of America - 27 May 2014

Edwards Matthew D, Symbor-Nagrabska Anna, Dollard Lindsey, Gifford David K, Fink Gerald R

Abstract excerpt

The measurement of any nonchromosomal genetic contribution to the heritability of a trait is often confounded by the inability to control both the chromosomal and nonchromosomal information in a population. We have designed a unique system in yeast where we can control both sources of information so that the phenotype of a single chromosomal polymorphism can be measured in the presence of different cytoplasmic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24825890
DOI: 10.1073/pnas.1407126111
PMCID: PMC4040555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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