Fungal prions.

doi:10.1016/B978-0-12-385883-2.00007-2

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Article

Fungal prions.

Progress in molecular biology and translational science - 1 Jan 2012

Staniforth Gemma L, Tuite Mick F

Abstract excerpt

For both mammalian and fungal prion proteins, conformational templating drives the phenomenon of protein-only infectivity. The conformational conversion of a protein to its transmissible prion state is associated with changes to host cellular physiology. In mammals, this change is synonymous with disease, whereas in fungi no notable detrimental effect on the host is typically observed. Instead, fungal prions can...

Topics

Amino Acid Sequence
Epigenesis, Genetic
Fungal Proteins
Fungi
Genes, Fungal
Models, Biological
Molecular Sequence Data
Mutation
Nitrogen
Prions
Transcription Factors
Translational Research, Biomedical

Source

Open in PubMed

Identifiers

PMID: 22482457
DOI: 10.1016/B978-0-12-385883-2.00007-2

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