Article
Vaccination has minimal impact on the intrahost diversity of H3N2 influenza viruses.
PLoS pathogens - 1 Jan 2017
Debbink Kari, McCrone John T, Petrie Joshua G, Truscon Rachel, Johnson Emileigh, Mantlo Emily K, Monto Arnold S, Lauring Adam S
Abstract excerpt
While influenza virus diversity and antigenic drift have been well characterized on a global scale, the factors that influence the virus' rapid evolution within and between human hosts are less clear. Given the modest effectiveness of seasonal vaccination, vaccine-induced antibody responses could serve as a potent selective pressure for novel influenza variants at the individual or community level. We used next...
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