Enhanced Genetic Characterization of Influenza A(H3N2) Viruses and Vaccine Effectiveness by Genetic Group, 2014-2015.

doi:10.1093/infdis/jiw181

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Article

Enhanced Genetic Characterization of Influenza A(H3N2) Viruses and Vaccine Effectiveness by Genetic Group, 2014-2015.

The Journal of infectious diseases - 1 Oct 2016

Flannery Brendan, Zimmerman Richard K, Gubareva Larisa V, Garten Rebecca J, Chung Jessie R, Nowalk Mary Patricia, Jackson Michael L, Jackson Lisa A, Monto Arnold S, Ohmit Suzanne E, Belongia Edward A, McLean Huong Q, Gaglani Manjusha, Piedra Pedro A, Mishin Vasiliy P, Chesnokov Anton P, Spencer Sarah, Thaker Swathi N, Barnes John R, Foust Angie, Sessions Wendy, Xu Xiyan, Katz Jacqueline, Fry Alicia M

Abstract excerpt

BACKGROUND: During the 2014-2015 US influenza season, expanded genetic characterization of circulating influenza A(H3N2) viruses was used to assess the impact of the genetic variability of influenza A(H3N2) viruses on influenza vaccine effectiveness (VE). METHODS: A novel pyrosequencing assay was used to determine genetic group, based on hemagglutinin (HA) gene sequences, of influenza A(H3N2) viruses from...

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PMID: 27190176
DOI: 10.1093/infdis/jiw181
PMCID: PMC5812259

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