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Article

Vaccine immune pressure influences viral population complexity of avian influenza virus during infection.

Veterinary microbiology - 1 May 2017

Milani Adelaide, Fusaro Alice, Bonfante Francesco, Zamperin Gianpiero, Salviato Annalisa, Mancin Marzia, Mastrorilli Eleonora, Hughes Joseph, Hussein Hussein A, Hassan Magdi, Mundt Egbert, Terregino Calogero, Cattoli Giovanni, Monne Isabella

Abstract excerpt

Vaccines are useful tools to control influenza A virus infection in poultry, but they need to be periodically reformulated to guarantee appropriate protection from infection and to limit viral replication and circulation, which could favour the emergence of new variants. In this study, a deep sequencing approach was used to characterize and follow the evolution of the hemagglutinin of the H5N1 highly pathogenic...

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PMID: 28619173
DOI: 10.1016/j.vetmic.2017.02.016

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