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Article

Susceptibility to Childhood Pneumonia: A Genome-Wide Analysis.

American journal of respiratory cell and molecular biology - 1 Jan 2017

Hayden Lystra P, Cho Michael H, McDonald Merry-Lynn N, Crapo James D, Beaty Terri H, Silverman Edwin K, Hersh Craig P

Abstract excerpt

Previous studies have indicated that in adult smokers, a history of childhood pneumonia is associated with reduced lung function and chronic obstructive pulmonary disease. There have been few previous investigations using genome-wide association studies to investigate genetic predisposition to pneumonia. This study aims to identify the genetic variants associated with the development of pneumonia during childhood...

Topics

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Child
Gene Regulatory Networks
Genetic Loci
Genetic Predisposition to Disease
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 27508494
DOI: 10.1165/rcmb.2016-0101OC
PMCID: PMC5248961

Genes

MATN1
MCPH1
PAK6
PHACTR1
PRR27
RAPGEF2

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