Classification of RNA structure change by 'gazing' at experimental data.

Abstract excerpt

MOTIVATION: Mutations (or Single Nucleotide Variants) in folded RiboNucleic Acid structures that cause local or global conformational change are riboSNitches. Predicting riboSNitches is challenging, as it requires making two, albeit related, structure predictions. The data most often used to experimentally validate riboSNitch predictions is Selective 2' Hydroxyl Acylation by Primer Extension, or SHAPE....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Classification
• Share to High-Throughput Nucleotide Sequencing
• Share to Nucleic Acid Conformation