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Article

VarScan2 analysis of de novo variants in monozygotic twins discordant for schizophrenia.

Psychiatric genetics - 1 Apr 2017

Reble Emma, Castellani Christina A, Melka Melkaye G, O'Reilly Richard, Singh Shiva M

Abstract excerpt

OBJECTIVES: Monozygotic twins with near-identical genotypes and discordance for complex diseases represent an exceptional resource to ascertain disease etiology. This strategy has been particularly effective with the availability of high-resolution complete individual genome sequencing. The challenge is using effective approaches to identify relevant differences that may cause or contribute toward disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28125460
DOI: 10.1097/YPG.0000000000000162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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