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Article

Restricted genetic diversity of HIV-1 subtype C envelope glycoprotein from perinatally infected Zambian infants.

PloS one - 18 Feb 2010

Zhang Hong, Tully Damien C, Hoffmann Federico G, He Jun, Kankasa Chipepo, Wood Charles

Abstract excerpt

BACKGROUND: Mother-to-child transmission of HIV-1 remains a significant problem in the resource-constrained settings where anti-retroviral therapy is still not widely available. Understanding the earliest events during HIV-1 transmission and characterizing the newly transmitted or founder virus is central to intervention efforts. In this study, we analyzed the viral env quasispecies of six mother-infant...

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Source

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Identifiers

PMID: 20174636
DOI: 10.1371/journal.pone.0009294
PMCID: PMC2823783

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Source receipt: pubmed, retrieved 7 Sept 2026.

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