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Article

Murine Autoimmune Optic Neuritis Is Not Phenotypically Altered by the Retinal Degeneration 8 Mutation.

Investigative ophthalmology & visual science - 1 Jan 2017

Stojic Aleksandar, Fairless Richard, Beck Susanne C, Sothilingam Vithiyanjali, Weissgerber Petra, Wissenbach Ulrich, Gimmy Valerie, Seeliger Mathias W, Flockerzi Veit, Diem Ricarda, Williams Sarah K

Abstract excerpt

Purpose: To investigate whether the presence of the retinal degeneration 8 (rd8) mutation in C57BL/6 mice alters the phenotype of autoimmune optic neuritis (AON). Methods: C57BL/6J and C57BL/6N mice were genotyped for the rd8 mutation and fundus analyses and examination of retinal layer morphology were performed in vivo by scanning laser ophthalmoscopy and optical coherence tomography. Visual function was...

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PMID: 28114593
DOI: 10.1167/iovs.16-20419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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