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Automated Antibody De Novo Sequencing and Its Utility in Biopharmaceutical Discovery

19 Jan 2017

Abstract excerpt

Applications of antibody de novo sequencing in the biopharmaceutical industry range from the discovery of new antibody drug candidates to identifying reagents for research and determining the primary structure of innovator products for biosimilar development. When murine, phage display, or patient-derived monoclonal antibodies against a target of interest are available, but the cDNA or the original cell line is...

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PMID: 28105549
DOI: 10.1007/s13361-016-1580-0

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