Article

Data mining antibody sequences for database searching in bottom-up proteomics

2024-02-14

Abstract excerpt

Mass spectrometry (MS)-based proteomics allows identifying and quantifying thousands of proteins but suffers from challenges when measuring human antibodies due to their vast variety. The mainly used bottom-up proteomics approaches rely on database searches that compare experimental values of peptides and their fragments to theoretical values derived from protein sequences in a database. While the human body can p...

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Literature Corpus work: b6398625-4e11-5ca8-9826-69dd707afca3
DOI: 10.1101/2024.02.13.580076

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