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Functional Promoter Polymorphisms of MMP-2 C-735T and MMP-9 C-1562T and Their Synergism with MMP-7 A-181G in Multiple Sclerosis.

Immunological investigations - 1 Aug 2016

Rahimi Zohreh, Abdan Zahra, Rahimi Ziba, Razazian Nazanin, Shiri Hadis, Vaisi-Raygani Asad, Shakiba Ebrahim, Vessal Mahmood, Moradi Mohammad-Taher

Abstract excerpt

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system. Matrix metalloproteinases (MMPs) play an important role in breakdown of blood-brain barrier, transmigration, and invasion of immune cells and formation of MS lesions. The aim of present study was to investigate the influence of MMP-2 C-735T and MMP-9 C-1562T variants and their synergism with MMP-7 A-181G on susceptibility to...

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PMID: 27409770
DOI: 10.1080/08820139.2016.1180303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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