Article
Pathogenicity of modified bat influenza virus with different M genes and its reassortment potential with swine influenza A virus.
The Journal of general virology - 1 Apr 2017
Yang Jianmei, Lee Jinhwa, Ma Jingjiao, Lang Yuekun, Nietfeld Jerome, Li Yuhao, Duff Michael, Li Yonghai, Yang Yuju, Liu Haixia, Zhou Bin, Wentworth David E, Richt Juergen A, Li Zejun, Ma Wenjun
Abstract excerpt
In our previous studies, the reassortant virus containing only the PR8 H1N1 matrix (M) gene in the background of the modified bat influenza Bat09 : mH1mN1 virus could be generated. However, whether M genes from other origins can be rescued in the background of the Bat09 : mH1mN1 virus and whether the resulting novel reassortant virus is virulent remain unknown. Herein, two reassortant viruses were generated in...
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