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Article

Virulence Determinants of Pandemic A(H1N1)2009 Influenza Virus in a Mouse Model

6 Dec 2012

Abstract excerpt

A novel swine-origin H1N1 influenza virus [A(H1N1)pdm09 virus] caused the 2009 influenza pandemic. Most patients exhibited mild symptoms similar to seasonal influenza, but some experienced severe clinical signs and, in the worst cases, died. Such differences in symptoms are generally associated with preexisting medical conditions, but recent reports indicate the possible involvement of viral factors in clinical...

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PMID: 23221570
DOI: 10.1128/jvi.01565-12

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