Article

Swine influenza A virus isolates containing the pandemic H1N1 origin matrix gene elicit greater disease in the murine model

2023-09-25

Abstract excerpt

<h4>ABSTRACT</h4> Since the 1990’s, endemic North American swine influenza A viruses (swFLUAV) contained an internal gene segment constellation referred to as the triple reassortment internal gene (TRIG) cassette. In 2009, the H1N1 pandemic (pdmH1N1) virus spilled back into swine, but did not become endemic. However, the pdmH1N1 did contribute the matrix gene segment (pdmM) to the swFLUAVs circulating in the pig...

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Literature Corpus work: 223c2da5-3ea1-58c1-a8fc-205e6133bc81
DOI: 10.1101/2023.09.25.559220

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