Article
Leptin receptor gene polymorphisms and morbid obesity in Mexican patients.
Hereditas - 1 Jan 2016
Rojano-Rodriguez Martin Edgardo, Beristain-Hernandez Jose Luis, Zavaleta-Villa Beatriz, Maravilla Pablo, Romero-Valdovinos Mirza, Olivo-Diaz Angelica
Abstract excerpt
BACKGROUND: Human obesity is due to a complex interaction among environmental, behavioral, developmental and genetic factors, including the interaction of leptin (LEP) and leptin receptor (LEPR). Several LEPR mutations and polymorphisms have been described in patients with early onset severe obesity and hyperphagic eating behavior; however, some contradictory findings have also been reported. In the present study...
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