Article
p.Q223R leptin receptor polymorphism associated with obesity in Brazilian multiethnic subjects.
American journal of human biology : the official journal of the Human Biology Council - 1 Jan 2000
Duarte Stenio Fernando Pimentel, Francischetti Emílio Antonio, Genelhu-Abreu Virgínia, Barroso Sergio Girão, Braga José Uéleres, Cabello Pedro Hernan, Pimentel Márcia Mattos Gonçalves
Abstract excerpt
Several genes play a major role in obese phenotypes, and studies suggest that genetic variations among individuals, as well as their lifestyles, may bring about different body compositions. Among these genes, LEP, which codifies leptin, and the LEPR gene encoding its receptor were extensively studied for variants that could explain the obese phenotype. The LEPR p.Q223R gene polymorphism was analyzed in a sample...
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