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Article

Leptin receptor gene K656N polymorphism is associated with low body fat levels and elevated high-density cholesterol levels in Mexican children and adolescents.

Endocrine research - 1 Jan 2012

Angel-Chávez Luis I, Tene-Pérez Carlos E, Castro Elena

Abstract excerpt

INTRODUCTION: This study evaluated the association between obesity and the K109R, Q223R, and K656N polymorphisms of the leptin receptor (LEPR) locus. Such polymorphisms cause changes in the extracellular extreme of the LEPR gene product and appear to be related to signal transduction toward the cell. SUBJECTS AND METHODS: A total of 128 participants between 6 and 17 years of age from a Mexican Mestizo population...

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Share to Adiposity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Leptin

Source

Identifiers

PMID: 22746211
DOI: 10.3109/07435800.2011.648360

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Leptin receptor gene K656N polymorphism is associated with low body fat levels and elevated high-density cholesterol levels in Mexican children and adolescents.PMID 22746211Read ↗

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