Article
Lack of mutations in the leptin receptor gene in severely obese children.
Arquivos brasileiros de endocrinologia e metabologia - 1 Apr 2012
Dias Natasha Favoretto, Fernandes Ariana Ester, Melo Maria Edna de, Reinhardt Heidi Lui, Cercato Cintia, Villares Sandra Mara Ferreira, Halpern Alfredo, Mancini Marcio C
Abstract excerpt
OBJECTIVE: To analyze the LEPR gene in obese children and to investigate the associations between molecular findings and anthropometric and metabolic features. SUBJECTS AND METHODS: Thirty-two patients were evaluated regarding anthropometric characteristics, blood pressure, heart rate, serum glucose, insulin, leptin levels, and lipid profile. The molecular study consisted of the amplification and automatic...
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