Article
Methylation specific targeting of a chromatin remodeling complex from sponges to humans.
Scientific reports - 17 Jan 2017
Cramer Jason M, Pohlmann Deborah, Gomez Fernando, Mark Leslie, Kornegay Benjamin, Hall Chelsea, Siraliev-Perez Edhriz, Walavalkar Ninad M, Sperlazza M Jeannette, Bilinovich Stephanie, Prokop Jeremy W, Hill April L, Williams David C
Abstract excerpt
DNA cytosine methylation and methyl-cytosine binding domain (MBD) containing proteins are found throughout all vertebrate species studied to date. However, both the presence of DNA methylation and pattern of methylation varies among invertebrate species. Invertebrates generally have only a single MBD protein, MBD2/3, that does not always contain appropriate residues for selectively binding methylated DNA....
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