Article
Multiple Sclerosis and EIF2B5: A Paradox or a Missing Link.
Advances in experimental medicine and biology - 1 Jan 2017
Zahoor Insha, Haq Ehtishamul, Asimi Ravouf
Abstract excerpt
Multiple sclerosis (MS) is an encumbering inflammatory condition of the central nervous system (CNS) caused by axonal demyelination. There is sufficient evidence suggesting role of eukaryotic translation initiation factor 2B (EIF2B) gene family encoding the five subunits of eIF2B complex-α, β, γ, δ and ε respectively, in causing vanishing white matter (VWM) disease of the brain. Incidentally researchers have...
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