Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Vero-cell-adapted vaccine donor strain of influenza A virus generated by serial passages.

Vaccine - 3 Jan 2015

Hu Weibin, Zhang Hong, Han Qinglin, Li Li, Chen Yixin, Xia Ningshao, Chen Ze, Shu Yuelong, Xu Ke, Sun Bing

Abstract excerpt

A cell culture-based vaccine production system is preferred for the large-scale production of influenza vaccines and has advantages for generating vaccines against highly pathogenic influenza A viruses. Vero cells have been widely used in human vaccine manufacturing, and the safety of these cells has been well demonstrated. However, the most commonly used influenza-vaccine donor virus, A/Puerto Rico/8/1934 (PR8)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Influenza A Virus, H1N1 Subtype
Share to Influenza A Virus, H3N2 Subtype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A Virus, H5N1 Subtype

Share to Influenza A Virus, H9N2 Subtype

Share to Influenza Vaccines

Share to Reassortant Viruses

Share to Serial Passage

Share to Virus Cultivation

Source

Identifiers

PMID: 25448099
DOI: 10.1016/j.vaccine.2014.11.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Vero-cell-adapted vaccine donor strain of influenza A virus generated by serial passages.PMID 25448099Read ↗

Development of high-yield influenza A virus vaccine viruses.Semantic proximity Read ↗

Generation of High-Yielding Influenza A Viruses in African Green Monkey Kidney (Vero) Cells by Reverse GeneticsSemantic proximity Read ↗

Single PA mutation as a high yield determinant of avian influenza vaccines.Semantic proximity Read ↗

Development of an Influenza A Master Virus for Generating High-Growth Reassortants for A/Anhui/1/2013(H7N9) Vaccine Production in Qualified MDCK Cells.Semantic proximity Read ↗

Development of a high-yield reassortant influenza vaccine virus derived from the A/Anhui/1/2013 (H7N9) strainSemantic proximity Read ↗

Cell culture-derived influenza vaccines from Vero cells: a new horizon for vaccine productionSemantic proximity Read ↗

Development of a new candidate H5N1 avian influenza virus for pre‐pandemic vaccine productionSemantic proximity Read ↗

Complete genome analysis of three live attenuated Rinderpest virus vaccine strains derived through serial passages in different culture systems.Semantic proximity Read ↗

Molecular signature of high yield (growth) influenza a virus reassortants prepared as candidate vaccine seeds.Semantic proximity Read ↗

Poliovirus-nonsusceptible Vero cell line for the World Health Organization global action planSemantic proximity Read ↗

An improved reverse genetics system for influenza A virus generation and its implications for vaccine productionSemantic proximity Read ↗

Eight-plasmid system for rapid generation of influenza virus vaccines.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.