Article

Vascular NRP2 triggers PNET angiogenesis by activating the SSH1-cofilin axis

2020-08-24

Abstract excerpt

<h4>Background: </h4> Angiogenesis is a critical step in the growth of pancreatic neuroendocrine tumors (PNETs) and may be a selective target for PNET therapy. However, PNETs are robustly resistant to current anti-angiogenic therapies that primarily target the VEGFR pathway. Thus, the mechanism of PNET angiogenesis urgently needs to be clarified. <h4>Methods:</h4> Dataset analysis was used to identify angiogenesis...

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Literature Corpus work: da75897f-4c71-569b-bbd8-ae3fa8d4712f
DOI: 10.21203/rs.3.rs-29079/v2

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