Article
The pharmacogenetics of antimalaria artemisinin combination therapy.
Expert opinion on drug metabolism & toxicology - 1 Oct 2011
Piedade Rita, Gil José Pedro
Abstract excerpt
INTRODUCTION: Plasmodium falciparum malaria is one of the world's most lethal infectious diseases, commanding millions of drug administrations per year. The pharmacogenetics of these drugs is poorly known, although its application can be pivotal for the optimized management of this disease. AREAS COVERED: The main components of artemisinin combination therapy (ACT), the worldwide main antimalarial strategy, are...
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