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Article

Pharmacogenetics of antimalarial drugs: effect on metabolism and transport.

The Lancet. Infectious diseases - 1 Dec 2009

Kerb Reinhold, Fux Richard, Mörike Klaus, Kremsner Peter G, Gil José Pedro, Gleiter Christoph H, Schwab Matthias

Abstract excerpt

The prevention and management of malaria is primarily based on the use of drugs. Clinical trials have however revealed that between individuals there is large variability in the pharmacokinetic profiles of many antimalarial drugs. The resulting variations in concentrations of the drug within plasma might lead to either suboptimum effectiveness or drug toxicity in some patients. The evidence is increasing that...

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PMID: 19926036
DOI: 10.1016/S1473-3099(09)70320-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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