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Article

Using fast-acting temperature-sensitive mutants to study cell division in Caenorhabditis elegans.

Methods in cell biology - 1 Jan 2017

Davies T, Sundaramoorthy S, Jordan S N, Shirasu-Hiza M, Dumont J, Canman J C

Abstract excerpt

Fast-acting temperature-sensitive (ts) mutations are powerful conditional tools for studying transient cellular processes such as cytokinesis. Fast-acting ts cytokinesis-defective mutants are functional at the permissive temperature; yet show a fully penetrant loss-of-function cytokinesis failure phenotype when upshifted to the restrictive temperature. Fast-acting ts mutations thus allow functional tunability and...

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PMID: 28065312
DOI: 10.1016/bs.mcb.2016.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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