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Article

Gene transcription is coordinated with, but not dependent on, cell divisions during C. elegans embryonic fate specification.

Development (Cambridge, England) - 1 Aug 2013

Nair Gautham, Walton Travis, Murray John Isaac, Raj Arjun

Abstract excerpt

Cell differentiation and proliferation are coordinated during animal development, but the link between them remains uncharacterized. To examine this relationship, we combined single-molecule RNA imaging with time-lapse microscopy to generate high-resolution measurements of transcriptional dynamics in Caenorhabditis elegans embryogenesis. We found that globally slowing the overall development rate of the embryo by...

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Identifiers

PMID: 23863485
DOI: 10.1242/dev.098012
PMCID: PMC3737719

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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