Article
Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans.
Nature methods - 1 Jul 2008
Chung Kwanghun, Crane Matthew M, Lu Hang
Abstract excerpt
Microscopy, phenotyping and visual screens are frequently applied to model organisms in combination with genetics. Although widely used, these techniques for multicellular organisms have mostly remained manual and low-throughput. Here we report the complete automation of sample handling, high-resolution microscopy, phenotyping and sorting of Caenorhabditis elegans. The engineered microfluidic system, coupled with...
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