Article
Phenotypic and suppressor analysis of defecation in clk-1 mutants reveals that reaction to changes in temperature is an active process in Caenorhabditis elegans.
Genetics - 1 Nov 2001
Branicky R, Shibata Y, Feng J, Hekimi S
Abstract excerpt
Mutations in the Caenorhabditis elegans maternal-effect gene clk-1 affect cellular, developmental, and behavioral timing. They result in a slowing of the cell cycle, embryonic and postembryonic development, reproduction, and aging, as well as of the defecation, swimming, and pharyngeal pumping cycles. Here, we analyze the defecation behavior in clk-1 mutants, phenotypically and genetically. When wild-type worms...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Chromosome Mapping
- Defecation
- Genetic Complementation Test
- Helminth Proteins
- Mutation
- Phenotype
- Suppression, Genetic
- Temperature
- Time Factors